| Long name: |
ALEXA FLUOR 555 Conjugated, FEZ2/Zygin2 Polyclonal Antibody |
| Also known as: |
Anti-FEZ2/Zygin2 PAb ALEXA FLUOR 555 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
555, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FEZ2/Zygin2 |
| Specificity: |
This is a highly specific antibody against FEZ2/Zygin2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FEZ2/Zygin2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
As component of the network of molecules that regulate cellular morphology and axon guidance machinery, Expressed mainly in brain, Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia, PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination, Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short, Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1, elegans UNC-76 mutants, the plasma membrane to the cytoplasm by activation of PKC zeta, which suggest a functional role in axonal outgrowth, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation, Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
553nm/568nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 555, Alexa Fluor |
| Gene target: |
FEZ2/Zygin2 |
| Short name: |
FEZ2/Zygin2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 555 |
| Alternative name: |
ALEXA FLUOR 555, fasciculation and elongation protein zeta 2 (zygin II)/Zygin2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
FEZ2 and IDBG-44299 and ENSG00000171055 and 9637, FEZ2 and IDBG-632353 and ENSBTAG00000009021 and 100299092, Fez2 and IDBG-198635 and ENSMUSG00000056121 and 225020, HUM3CL, multiple, protein binding, this GO :0005515 and protein binding and molecular function this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, fasciculation and elongation protein zeta 2 (zygin II) |
| Identity: |
3660 |
| Gene: |
FEZ2 |
More about : FEZ2 |
| Long gene name: |
fasciculation and elongation protein zeta 2 |
| Synonyms name: |
zygin II |
| Locus: |
2p22, 2 |
| Discovery year: |
1999-12-14 |
| GenBank acession: |
U60061 |
| Entrez gene record: |
9637 |
| Pubmed identfication: |
9096408 |
| Havana BLAST/BLAT: |
OTTHUMG00000152148 |