| Long name: |
Biotin Conjugated, FEZ2/Zygin2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FEZ2/Zygin2 |
| Specificity: |
This is a highly specific antibody against FEZ2/Zygin2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human FEZ2/Zygin2 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As component of the network of molecules that regulate cellular morphology and axon guidance machinery, Expressed mainly in brain, Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia, PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination, Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short, Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1, elegans UNC-76 mutants, the plasma membrane to the cytoplasm by activation of PKC zeta, which suggest a functional role in axonal outgrowth, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation, Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FEZ2/Zygin2 Conjugated |
| Short name: |
Conjugated, FEZ2/Zygin2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, fasciculation and elongation protein zeta 2 (zygin II)/Zygin2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
FEZ2 and IDBG-44299 and ENSG00000171055 and 9637, FEZ2 and IDBG-632353 and ENSBTAG00000009021 and 100299092, Fez2 and IDBG-198635 and ENSMUSG00000056121 and 225020, HUM3CL, multiple, protein binding, this GO :0005515 and protein binding and molecular function this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, fasciculation and elongation protein zeta 2 (zygin II) |
| Identity: |
3660 |
| Gene: |
FEZ2 |
More about : FEZ2 |
| Long gene name: |
fasciculation and elongation protein zeta 2 |
| Synonyms name: |
zygin II |
| Locus: |
2p22, 2 |
| Discovery year: |
1999-12-14 |
| GenBank acession: |
U60061 |
| Entrez gene record: |
9637 |
| Pubmed identfication: |
9096408 |
| Havana BLAST/BLAT: |
OTTHUMG00000152148 |