| Long name: |
ALEXA FLUOR 488 Conjugated, ENSA/ARPP-19 Polyclonal Antibody |
| Also known as: |
Anti-ENSA/ARPP-19 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ENSA/ARPP-19 |
| Specificity: |
This is a highly specific antibody against ENSA/ARPP-19 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ENSA/ARPP-19 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
ENSA/ARPP-19, ENSA/ARPP-19 is an endogenous regulator of the Î, ENSA/ARPP-19 is encoded by a gene located on human chromosome 1q21, ENSA/ARPP-19 is phosphorylated by PKA and exists as eight alternatively spliced isoforms, It is suggested that ENSA/ARPP-19 expression is decreased in brains of both Alzheimer's disease (AD) and Down's syndrome patients, Widely expressed with high levels in skeletal muscle and brain and lower levels in pancreas, also known as ARPP-19e, cells, is a 121 amino acid protein that localizes to the cytoplasm and belongs to the endosulfine family, ², ², -cell K(ATP) channels and reduces K(ATP) channel currents by inhibiting sulfonylurea from binding to the receptor thereby stimulating insulin secretion by pancreatic Î, 3, Sulfonylureas are a class of drugs commonly used in the management of noninsulin-dependent diabetes mellitus |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
MGC4319 MGC8394 MGC78563 ARPP-19e |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ENSA/ARPP-19 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
ENSA/ARPP-19 |
| Short name: |
ENSA/ARPP-19 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, ENSA/ARPP-19 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
3360 |
| Gene: |
ENSA |
More about : ENSA |
| Long gene name: |
endosulfine alpha |
| Locus: |
1q21, 3 |
| Discovery year: |
1998-08-21 |
| GenBank acession: |
X99906 |
| Entrez gene record: |
2029 |
| Pubmed identfication: |
9653196 |
| RefSeq identity: |
NM_207042 |
| Havana BLAST/BLAT: |
OTTHUMG00000035004 |