| Long name: |
Rad53/SPK1 Primary Polyclonal Antibody |
| Also known as: |
Rad53/SPK1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Rad53/SPK1 |
| Specificity: |
This is a highly specific antibody against Rad53/SPK1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Rad53/SPK1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Activation of Rad53 is regulated by Mec1 (also known as Esr1 and Sad3), Checkpoints exist at several cell cycle phase transitions to maintain this genetic integrity, Dun1, Mec2 or Sad1) is essential for both G2 and S phase arrest, Pds1 and Mad2 both regulate checkpoints associated with incomplete spindle replication (7, Pol2 (also known as Dun2), Rad17, Rad24 and Mec3 are involved in activating the G1 and G2 checkpoints (1â, Rad9, The protein kinase Rad53 (also designated Spk1, a homolog of the human ATM protein (6), allowing the damaged DNA to be repaired prior to replication, another protein kinase, encoding the catalytic subunit of DNA polymerase epsilon, plays a role in activating the S phase checkpoint (5), plays a role in transducing the DNA damage signal (9), &euro, &ldquo, 4), 8), DNA damage results in the arrest of cell cycle progression |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CHK2 homolog, MEC2, RAD53, RAD53_YEAST, SPK1, Serine protein kinase 1, Serine-protein kinase 1, Serine/threonine-protein kinase RAD53, CHEK2 homolog |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Rad53/SPK1 |
| Short name: |
Rad53/SPK1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Rad53/SPK1 (Antibody to) |
| Alternative technique: |
antibodies |