| Long name: |
FITC Conjugated, Prion protein PrP/CD230 Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Prion protein PrP/CD230 |
| Specificity: |
This is a highly specific antibody against Prion protein PrP/CD230 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Prion protein PrP/CD230 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase, May be required for neuronal myelin sheath maintenance, May play a role in iron uptake and iron homeostasis (By similarity), May play a role in neuronal development and synaptic plasticity, Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro), The function of PrP is still under debate |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CD230 PRP AltPrP |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Prion protein PrP/CD230 Conjugated |
| Short name: |
FITC Conjugated, Prion protein PrP/CD230 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Prion protein PrP/CD230 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9449 |
| Gene: |
PRNP |
More about : PRNP |
| Long gene name: |
prion protein |
| Synonyms gene: |
PRIP GSS CJD |
| Synonyms gene name: |
prion protein (p27-30) |
| Synonyms name: |
Creutzfeldt-Jakob disease Gerstmann-Strausler-Scheinker syndrome fatal familial insomnia p27-30 |
| Locus: |
20p13 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M13899 |
| Entrez gene record: |
5621 |
| RefSeq identity: |
NM_000311 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000031786 |
| Locus Specific Databases: |
Prion Protein/CJD database |