| Long name: |
Cy7 Conjugated, TTBK2/SCA11 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy7 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
TTBK2/SCA11 |
| Specificity: |
This is a highly specific antibody against TTBK2/SCA11 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human TTBK2/SCA11 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the SCA11 protein are the cause of the disorder spinocerebellar ataxia type 11 (SCA11), Existing as three alternatively spliced isoforms, It is a relatively benign, Patients show progressive incoordination of gait and often poor coordination of hands, Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders, The SCA11 disorder is an autosomal dominant cerebellar ataxia (ADCA), The SCA11 gene, The SCA11 protein has also been implicated in Alzheimer disease and in tangle formation, and maps to human chromosome 15q15, chicken and zebrafish, comprising of 16 exons, cow, dog, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord, late-onset, mouse, produces a 5, rat, slowly progressive neurologic disorder, speech and eye movements, the SCA11 gene is conserved in chimpanzee, 2, 244 amino acid protein that belongs to the protein kinase superfamily and the CK1 Ser/Thr protein kinase family, 6-kb transcript in which the longest open reading frame is 3, 732 nucleotides, SCA11 is a 1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
743nm/767nm |
| Synonyms: |
KIAA0847 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths |
| Gene target: |
TTBK2/SCA11 Conjugated |
| Short name: |
Conjugated, TTBK2/SCA11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Cy7 |
| Alternative name: |
cyanine 7 coupled, TTBK2/SCA11 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19141 |
| Gene: |
TTBK2 |
More about : TTBK2 |
| Long gene name: |
tau tubulin kinase 2 |
| Synonyms gene: |
SCA11 |
| Synonyms gene name: |
spinocerebellar ataxia 11 |
| Locus: |
15q15, 2 |
| Discovery year: |
2003-05-28 |
| GenBank acession: |
AB020654 |
| Entrez gene record: |
146057 |
| Pubmed identfication: |
10048485 |
| RefSeq identity: |
NM_173500 |
| Havana BLAST/BLAT: |
OTTHUMG00000175802 |