Agrin Antibody, ALEXA FLUOR 488

Catalog number:	bs-1176R-A488 Buy Now
Price:	645 €
Supplier:	acr
Product name:	Agrin Antibody, ALEXA FLUOR 488
Quantity:	0,5 mg
Related search:	agrin alexa antibody fluor antibodies gene region domain induces

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Long name:	ALEXA FLUOR 488 Conjugated, Agrin Polyclonal Antibody
Also known as:	Anti-Agrin PAb ALEXA FLUOR 488
Category:	Conjugated Primary Antibodies
Conjugated with:	488, ALEXA FLUOR®
Host Organism:	Rabbit (Oryctolagus cuniculus)
Target Antigen:	Agrin
Specificity:	This is a highly specific antibody against Agrin
Modification:	Unmodified
Modification Site:	None
Clonality:	Polyclonal
Clone:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic peptide derived from mouse Agrin
Gene ID Number:	375790
Tested applications:	IF(IHC-P)
Recommended dilutions:	IF(IHC-P)(1:50-200)
Crossreactivity:	Rat, Mouse
Cross-reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen:	Agrin, Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction, MuSK and Rapsyn are all essential components for AChR aggregation, The C-terminal region of agrin is released into the medium, The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components, The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin, This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites, increasing the predicted MW from 200kDa to ~600kDa, interacts with receptors on the muscle surface and induces AChR aggregation, through an unknown mechanism, Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction
Purification:	Purified by Protein A
Storage conditions:	50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission:	499nm/519nm
Synonyms:	AGRIN
Properties:	ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Agrin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation:	Alexa Fluor
Gene target:	Agrin
Short name:	Agrin Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Label:	ALEXA FLUOR 488
Alternative name:	ALEXA FLUOR 488, Agrin (Antibody to)
Alternative technique:	antibodies
Identity:	329
Gene:	AGRN | More about : AGRN
Long gene name:	agrin
Synonyms name:	agrin proteoglycan
Locus:	1p36, 33
Discovery year:	1992-02-14
GenBank acession:	XM_372195
Entrez gene record:	375790
Pubmed identfication:	1851019 12270958
RefSeq identity:	NM_198576
Classification:	Proteoglycans
Havana BLAST/BLAT:	OTTHUMG00000040778
Locus Specific Databases:	Leiden Muscular Dystrophy pages LRG_198

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