Agrin Antibody

Catalog number:	bs-1176R Buy Now
Price:	499 €
Supplier:	abbex
Product name:	Agrin Antibody
Quantity:	100 μg
Other quantities:	1 x 1 vial 1382€
Related search:	agrin antibody antibodies gene region agrn kda

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Long name:	Agrin Primary Polyclonal Antibody
Also known as:	Agrin PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Agrin
Specificity:	This is a highly specific antibody against Agrin
Modification(s):	None
Modification site(s):	Unmodified antibody
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic peptide derived from mouse Agrin
Gene ID number:	375790
Tested Applications:	IF(IHC-P), IHC-P
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity:	Rat, Mouse
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Agrin, Agrin is an essential extracellular matrix component which promotes clustering of nicotinic acetylcholine receptors (nAChRs) and other proteins during development at the neuromuscular junction, MuSK and Rapsyn are all essential components for AChR aggregation, The C-terminal region of agrin is released into the medium, The N-terminal region anchors agrin to the extracellular matrix via other basal membrane components, The central region contains two O-linked glycosylation sites and a domain homologous to domain III of laminin, This region also contains a protease inhibitor domain and glycosaminoglycan attachment sites, increasing the predicted MW from 200kDa to ~600kDa, interacts with receptors on the muscle surface and induces AChR aggregation, through an unknown mechanism, Agrin is a neuronal aggregating factor that induces the aggregation of acetylcholine receptors and other postsynaptic proteins on muscle fibers and is crucial for the formation of the neuromuscular junction
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	AGRIN_HUMAN, AGRIN_MOUSE, AGRN, Agrin proteoglycan, FLJ45064, OTTHUMP00000044043, AGRIN
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Agrin
Short name:	Agrin Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	Agrin (Antibody to)
Alternative technique:	antibodies
Identity:	329
Gene:	AGRN | More about : AGRN
Long gene name:	agrin
Synonyms:	AGRIN
Synonyms name:	agrin proteoglycan
Locus:	1p36, 33
Discovery year:	1992-02-14
GenBank acession:	XM_372195
Entrez gene record:	375790
Pubmed identfication:	1851019 12270958
RefSeq identity:	NM_198576
Classification:	Proteoglycans
Havana BLAST/BLAT:	OTTHUMG00000040778
Locus Specific Databases:	Leiden Muscular Dystrophy pages LRG_198

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