| Long name: |
RNF135 Primary Polyclonal Antibody |
| Also known as: |
RNF135 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RNF135 |
| Specificity: |
This is a highly specific antibody against RNF135 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF135 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, Multiple isoforms of RNF135 exist due to alternative splicing events, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, RNF135 (RING finger protein 135), RNF135 may play a role in transcriptional regulation and protein degradation events, Via its RING-type zinc finger, also known as L13, facial dysmorphism and increased weight and height, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MGC13061, RN135_HUMAN , ring finger protein 135, L13 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RNF135 |
| Short name: |
RNF135 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ring finger protein 135 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BT, Cytoplasm, RNF135 and IDBG-39370 and ENSG00000181481 and 84282, Rnf135 and IDBG-204021 and ENSMUSG00000020707 and 71956, metal ion binding, this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0008270 and zinc ion binding and molecular function this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0032480 and negative regulation of type I interferon production and biological process this GO :0032728 and positive regulation of interferon-beta production and biological process this GO :0043021 and ribonucleoprotein complex binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045088 and regulation of innate immune response and biological process this GO :0046872 and metal ion binding and molecular function, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0016874 : ligase activity and also this GO :0043021 : ribonucleoprotein complex binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0016874 : ligase activity, this GO :0043021 : ribonucleoprotein complex binding, this GO :0046872 : metal ion binding, 65952 and IDBG-631087 and ENSBTAG00000017225 and 511125, ring finger protein 135 |
| Identity: |
21158 |
| Gene: |
RNF135 |
More about : RNF135 |
| Long gene name: |
ring finger protein 135 |
| Synonyms: |
MGC13061 |
| Synonyms name: |
riplet |
| Locus: |
17q11, 2 |
| Discovery year: |
2003-05-21 |
| GenBank acession: |
AJ496729 |
| Entrez gene record: |
84282 |
| Pubmed identfication: |
11468690 19017631 |
| RefSeq identity: |
NM_032322 |
| Classification: |
Ring finger proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000132867 |
| Locus Specific Databases: |
LOVD - Leiden Open Variation Database |