| Long name: |
GDAP1 Primary Polyclonal Antibody |
| Also known as: |
GDAP1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GDAP1 |
| Specificity: |
This is a highly specific antibody against GDAP1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GDAP1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Although it shares the carboxy and amino-terminal glutathione S-transferase domains, GDAP1 is characterized as a GST-like protein because it contains an extended GST domain II and a predicted transmembrane domain, GDAP1 may function in a signal transduction pathway that is responsible for ganglioside-induced neurite differentiation and also may play a role in protecting myelin membranes from free-radical damage, Mutations in the gene encoding GDAP1 is the cause of many forms of Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system that is characterized by reduced nerve conduction velocities, slow progressive distal muscle atrophy and absent deep tendon reflexes, two characteristics which are unusual for GST family members, Glutathione S-transferases (GSTs) function to conjugate reduced glutathione to many exogenous and endogenous hydrophobic electrophiles |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
GDAP1, GDAP1_HUMAN, Ganglioside-induced dferentiation-associated protein 1, Ganglioside induced dferentiation associated protein 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GDAP1 |
| Short name: |
GDAP1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GDAP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
15968 |
| Gene: |
GDAP1 |
More about : GDAP1 |
| Long gene name: |
ganglioside induced differentiation associated protein 1 |
| Synonyms gene: |
CMT4A |
| Synonyms gene name: |
Charcot-Marie-Tooth neuropathy 4A |
| Synonyms: |
CMT4 CMT2K |
| Locus: |
8q21, 11 |
| Discovery year: |
2001-06-25 |
| Entrez gene record: |
54332 |
| Pubmed identfication: |
8268915 11743579 |
| RefSeq identity: |
NM_018972 |
| Havana BLAST/BLAT: |
OTTHUMG00000164509 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_244 |