| Long name: |
FITC Conjugated, CCR4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CCR4 |
| Specificity: |
This is a highly specific antibody against CCR4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
200-250/360 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human CCR-4 |
| Gene ID number: |
1233 |
| Swiss Prot: |
P51679 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates, In the CNS, The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system, could mediate hippocampal-neuron survival, High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
CCR4 KIAA1194 Ccr4a |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CCR4 Conjugated |
| Short name: |
FITC Conjugated, CCR4 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, chemokine (C-C motif) receptor 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C-C chemokine receptor activity, CC-CKR-4 and CD194 and ChemR13 and CKR4 and CMKBR4 and HGCN:14099 and K5-5, CCR4 and IDBG-23908 and ENSG00000183813 and 1233, CCR4 and IDBG-644121 and ENSBTAG00000034883 and 100851774, Ccr4 and IDBG-203512 and ENSMUSG00000047898 and 12773, Cell surfaces, this GO :0001764 and neuron migration and biological process this GO :0002507 and tolerance induction and biological process this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0006955 and immune response and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0009314 and response to radiation and biological process this GO :0009617 and response to bacterium and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016493 and C-C chemokine receptor activity and molecular function this GO :0043025 and neuronal cell body and cellular component this GO :0045087 and innate immune response and biological process this GO :0046677 and response to antibiotic and biological process this GO :0050927 and positive regulation of positive chemotaxis and biological process this GO :0070098 and chemokine-mediated signaling pathway and biological process, this GO :0004930 : G-protein coupled receptor activity, this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0016493 : C-C chemokine receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0016493 : C-C chemokine receptor activity, 408019, chemokine (C-C motif) receptor 4 |
| Identity: |
14099 |
| Gene: |
CNOT6 |
More about : CNOT6 |
| Long gene name: |
CCR4-NOT transcription complex subunit 6 |
| Synonyms gene name: |
CCR4-NOT transcription complex, subunit 6 |
| Locus: |
5q35, 3 |
| Discovery year: |
2001-03-30 |
| GenBank acession: |
AB033020 |
| Entrez gene record: |
57472 |
| Pubmed identfication: |
11889047 |
| RefSeq identity: |
NM_015455 |
| Classification: |
CCR4-NOT transcription complex |
| Havana BLAST/BLAT: |
OTTHUMG00000130935 |