| Long name: |
Aggrecan Primary Polyclonal Antibody |
| Also known as: |
Aggrecan PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Aggrecan |
| Specificity: |
This is a highly specific antibody against Aggrecan |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
180-230/2415 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Aggrecan |
| Swiss Prot: |
P16112 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Aggrecan accounts for the compressive stiffness and resilience of the hyaline cartilage, Aggrecan in cartilage forms aggregates with hyaluronan and link protein, Aggrecan is a complex multidomain macromolecule that undergoes extensive processing and post-translational modification, Aggrecan is a member of the chondroitin sulphate proteoglycan family, Brevican is a brain proteoglycan of the aggrecan/versican/neurocan family, In the adult brain, Many forms of inflammatory arthritis are shown to be accompanied with aggrecan degradation and loss from the cartilage, aggrecan, embedded in a collagen network, is the predominant proteoglycan present in cartilage, neurocan and brevican, the brevican core protein undergoes proteolytic cleavage and exists as a full-length form a carboxy-terminal fragment and an amino-terminal fragment, which also includes versican/PG-M, The large chondroitin sulfate proteoglycan |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BEHAB, Brain enriched hyaluronan binding protein, Brevican core protein, Brevican core protein isoform 1, Brevican core protein isoform 2, Brevican proteoglycan, CSPG7, Chondroitin sulfate proteoglycan 7, Chondroitin sulfate proteoglycan BEHAB, MGC13038, BCAN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Aggrecan |
| Short name: |
Aggrecan Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Aggrecan (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7338 |
| Gene: |
MSK16 |
More about : MSK16 |
| Long gene name: |
aggrecan |
| Synonyms gene: |
CSPG1 AGC1 |
| Synonyms gene name: |
chondroitin sulfate proteoglycan 1 aggrecan 1 |
| Synonyms: |
CSPGCP ACAN |
| Synonyms name: |
aggrecan proteoglycan |
| Locus: |
15q26, 1 |
| Discovery year: |
1992-06-17 |
| GenBank acession: |
M55172 |
| Entrez gene record: |
176 |
| Pubmed identfication: |
1985970 |
| RefSeq identity: |
NM_001135 |
| Classification: |
Sushi domain containing Hyalectan proteoglycans V-set domain containing C-type lectin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000171989 |