| Long name: |
FITC Conjugated, APBA2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
APBA2 |
| Specificity: |
This is a highly specific antibody against APBA2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human APBA2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Multiple splice varitents of X11 have been identified, The Beta-Amyloid precursor is known to interact with several proteins, The neuronal, X11 Beta (Mint 2) and X11 Gamma(Mint 3), X11 binds specifically to the YENPTY motif, including X11 Alpha (also designated Mint 1), including X11 and the G heterotrimetric protein APP-BP1, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways, transmembrane protein X11 is known to bind to the â, which is involved in the internalization of Beta-APP, &circ, &euro, «, &trade, -Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimerâ, s disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
D15S1518E LIN-10 MGC:14091 HsT16821 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APBA2 Conjugated |
| Short name: |
FITC Conjugated, APBA2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, APBA2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
579 |
| Gene: |
APBA2 |
More about : APBA2 |
| Long gene name: |
amyloid beta precursor protein binding family A member 2 |
| Synonyms gene: |
X11L MINT2 |
| Synonyms gene name: |
X11-like amyloid beta (A4) precursor protein-binding, family A, family A, member 2 , member 2 (X11-like) amyloid beta (A4) precursor protein-binding |
| Locus: |
15q13, 1 |
| Discovery year: |
1997-06-25 |
| GenBank acession: |
AB014719 |
| Entrez gene record: |
321 |
| Pubmed identfication: |
8955346 |
| RefSeq identity: |
NM_005503 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129255 |