| Long name: |
APBA2 Primary Polyclonal Antibody |
| Also known as: |
APBA2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
APBA2 |
| Specificity: |
This is a highly specific antibody against APBA2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human APBA2 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Multiple splice varitents of X11 have been identified, The Beta-Amyloid precursor is known to interact with several proteins, The neuronal, X11 Beta (Mint 2) and X11 Gamma(Mint 3), X11 binds specifically to the YENPTY motif, including X11 Alpha (also designated Mint 1), including X11 and the G heterotrimetric protein APP-BP1, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways, transmembrane protein X11 is known to bind to the â, which is involved in the internalization of Beta-APP, &circ, &euro, «, &trade, -Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimerâ, s disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APBA2, APBA2_HUMAN, Amyloid beta A4 precursor protein-binding family A member 2, D15S1518E, HsT16821, LIN 10, Mint 2, Mint-2, Neuron-specic X11L protein, Neuronal Munc18-1-interacting protein 2, Phosphotyrosine binding/interacting domain PTB bearing protein, X11 beta, X11l, Adapter protein X11beta |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
APBA2 |
| Short name: |
APBA2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
APBA2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
579 |
| Gene: |
APBA2 |
More about : APBA2 |
| Long gene name: |
amyloid beta precursor protein binding family A member 2 |
| Synonyms gene: |
X11L MINT2 |
| Synonyms gene name: |
X11-like amyloid beta (A4) precursor protein-binding, family A, family A, member 2 , member 2 (X11-like) amyloid beta (A4) precursor protein-binding |
| Synonyms: |
D15S1518E LIN-10 MGC:14091 HsT16821 |
| Locus: |
15q13, 1 |
| Discovery year: |
1997-06-25 |
| GenBank acession: |
AB014719 |
| Entrez gene record: |
321 |
| Pubmed identfication: |
8955346 |
| RefSeq identity: |
NM_005503 |
| Classification: |
PDZ domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129255 |