| Long name: |
FITC Conjugated, CALHM1/FAM26C Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CALHM1/FAM26C |
| Specificity: |
This is a highly specific antibody against CALHM1/FAM26C |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CALHM1/FAM26C |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
CALHM1 co-localizes with GRP 78 to the endoplasmic reticulum, CALHM1 homomultimerizes and shares strong sequence similarities with the selectivity filter of the NMDA receptor, CALHM1 may be a pore-forming ion channel that controls cytosolic Ca2+ permeability and cytosolic Ca2+ concentration in the cell, CALHM1 may be a potential factor involved in the pathogenesis of Alzheimer's disease, It is suggested that CALHM1 regulates amyloid precursor protein proteolysis and aggregated amyloid-beta peptides levels in a Ca2+ dependent manner, Predominantly expressed in adult brain, which generates a large Ca2+ conductance across the plasma membrane, CALHM1 is a 346 amino acid multi-pass endoplasmic reticulum membrane protein that belongs to the FAM26 family |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CALHM1/FAM26C Conjugated |
| Short name: |
FITC Conjugated, CALHM1/FAM26C Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, CALHM1/FAM26C (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23494 |
| Gene: |
CALHM1 |
More about : CALHM1 |
| Long gene name: |
calcium homeostasis modulator 1 |
| Synonyms gene: |
FAM26C |
| Synonyms gene name: |
family with sequence similarity 26, member C |
| Locus: |
10q24, 33 |
| Discovery year: |
2004-05-27 |
| GenBank acession: |
BC036208 |
| Entrez gene record: |
255022 |
| Pubmed identfication: |
18585350 |
| RefSeq identity: |
NM_001001412 |
| Havana BLAST/BLAT: |
OTTHUMG00000018991 |