| Long name: |
TBR1 Primary Polyclonal Antibody |
| Also known as: |
TBR1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TBR1 |
| Specificity: |
This is a highly specific antibody against TBR1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TBR1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
CASK acts as a coactivator of TBR-1 to induce transcription of T-element containing genes, CASK can interact with TBR-1, CASK enters into the nucleus and binds to a specific DNA sequence (the T-element) in a complex with TBR-1, CASK is concentrated at neuronal synapses and binds to the cell-surface proteins, CASK/LIN-2, Chicken genes homolgous to these mouse genes are expressed in topologically comparable patterns during development, In adult rat brain, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium, T-brain-1 (TBR-1) mRNA is largely restricted to the cerebral cortex, TBR-1, TBR-1, The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains, Thus, a membrane-associated guanylate kinase, during embryogenesis, encodes a putative transcription factor related to the Brachyrury (T) gene that is expressed only in postmitotic cells, including reelin (5), is required for EGFR localization and signaling, it defines different regions that give rise to the palecortex, limbic cortex and neocortex (1-3), suggesting that mouse and chicken may have similar histogenetic specification processes and field homologies (4), where, which is involved in forebrain development, A novel murine and human gene |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium, T-brain-1 TBR-1 mRNA is largely restricted to the cerebral cortex, TBR-1, TBR-1, The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains, during embryogenesis, encodes a putative transcription factor related to the Brachyrury T gene that is expressed only in postmitotic cells, it defines dferent regions that give rise to the palecortex, limbic cortex and neocortex 1-3, where, A novel murine and human gene |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TBR1 |
| Short name: |
TBR1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TBR1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11590 |
| Gene: |
TBR1 |
More about : TBR1 |
| Long gene name: |
T-box, brain 1 |
| Synonyms gene name: |
1 , T-box, brain |
| Locus: |
2q24, 2 |
| Discovery year: |
1999-12-14 |
| GenBank acession: |
U49250 |
| Entrez gene record: |
10716 |
| Pubmed identfication: |
7619531 |
| RefSeq identity: |
NM_006593 |
| Classification: |
T-boxes |
| Havana BLAST/BLAT: |
OTTHUMG00000153888 |