Dab1 (Tyr198) Antibody

Catalog number:	bs-11548R Buy Now
Price:	326 €
Supplier:	acr
Product name:	Dab1 (Tyr198) Antibody
Quantity:	30 Вµl
Related search:	dab tyr antibody antibodies protein disabled term

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Long name:	Dab1 (Tyr198) Primary Polyclonal Antibody
Also known as:	Dab1 (Tyr198) PAb
Category:	Primary Antibodies
Conjugation:	Unconjugated
Target Antigen:	Dab1 Tyr198
Specificity:	This is a highly specific antibody against Dab1 Tyr198
Modification(s):	Phosphorylation
Modification site(s):	Tyr198
Clonality:	Polyclonal antibody
Clone number:	Polyclonal antibody
Concentration:	1ug per 1ul
Source:	KLH conjugated synthetic phosphopeptide derived from human Dab1 around the phosphorylation site of Tyr198 [V(p-Y)QY]
Tested Applications:	IF(IHC-P), IHC-P, WB
Recommended dilutions:	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity:	Mouse, Rat, Human
Cross reactive species details:	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen:	Dab1 has been shown to interact with the SH2 domains of Src, Dab2 (also designated DOC-2) is a mitogen-responsive phosphoprotein that binds the SH3 domain of Grb2, Evidence suggests that Dab1 functions downstream of Reelin in a signaling pathway involved in positioning cells in the developing brain (4), Fyn and Abl (1), Mutations in Dab1 result in widespread abnormalities in the brain, Reelin is a secreted protein thought to play a role in directing migrating neurons (3), This cytoplasmic protein is tyrosine-phosphorylated during rapid expansion of the developing nervous system, a homolog of the Drosophila Disabled protein, and it is thought to be a negative regulator of growth (5), and it is thought to interact with other proteins via a domain similar to the PTB domains of the Shc family, is an adaptor protein involved in neural development, similar to those seen in Reelin mutants (2), Dab1
Purification method:	This antibody was purified via Protein A
Storage conditions:	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names:	DAB1_HUMAN, Dab 1, Dab-1, Dab1, Dab1 Tyr198 , Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari, Dab1 phospho Y198
Properties:	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target:	Dab1 (Tyr198)
Short name:	Dab1 (Tyr198) Antibody
Technique:	antibodies against human proteins, antibodies for, Antibody
Alternative name:	disabled homolog 1 (Drosophila) (Tyr198) (Antibody to)
Alternative technique:	antibodies

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