| Long name: |
Dab1 Primary Polyclonal Antibody |
| Also known as: |
Dab1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Dab1 |
| Specificity: |
This is a highly specific antibody against Dab1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Dab1 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Dab1 has been shown to interact with the SH2 domains of Src, Dab2 (also designated DOC-2) is a mitogen-responsive phosphoprotein that binds the SH3 domain of Grb2, Evidence suggests that Dab1 functions downstream of Reelin in a signaling pathway involved in positioning cells in the developing brain (4), Fyn and Abl (1), Mutations in Dab1 result in widespread abnormalities in the brain, Reelin is a secreted protein thought to play a role in directing migrating neurons (3), This cytoplasmic protein is tyrosine-phosphorylated during rapid expansion of the developing nervous system, a homolog of the Drosophila Disabled protein, and it is thought to be a negative regulator of growth (5), and it is thought to interact with other proteins via a domain similar to the PTB domains of the Shc family, is an adaptor protein involved in neural development, similar to those seen in Reelin mutants (2), Dab1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DAB1_HUMAN, Dab 1, Dab-1, Dab1, Disabled homolog 1, Disabled homolog 1 Drosophila, Scm, Scr, Scrambler, Yot, Yotari |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Dab1 |
| Short name: |
Dab1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
disabled homolog 1 (Drosophila) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
49443 |
| Gene: |
DAB1-AS1 |
More about : DAB1-AS1 |
| Long gene name: |
DAB1 antisense RNA 1 |
| Locus: |
1p32, 2 |
| Discovery year: |
2013-12-03 |
| Entrez gene record: |
101926890 |
| Havana BLAST/BLAT: |
OTTHUMG00000008286 |