| Long name: |
ALEXA FLUOR 488 Conjugated, CDKL5 Polyclonal Antibody |
| Also known as: |
Anti-CDKL5 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CDKL5 |
| Specificity: |
This is a highly specific antibody against CDKL5 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CDKL5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Another family of proteins, CDKL5 (cyclin-dependent kinase-like 5) is a 1030 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family, CDKL5 is thought to play a role in cell cycle regulation, Cdk inhibitors, Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression, Defects in CDKL5 are a cause of several disorders, Expressed in brain, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity, kidney, lung, ovary, pancreas and testis, placenta, prostate, such as X-linked infantile spasm syndrome and Rett syndrome, Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin-dependent kinases (Cdks) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
EIEE2 CFAP247 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the CDKL5 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
CDKL5 |
| Short name: |
CDKL5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, CDKL5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
11411 |
| Gene: |
CDKL5 |
More about : CDKL5 |
| Long gene name: |
cyclin dependent kinase like 5 |
| Synonyms gene: |
STK9 |
| Synonyms gene name: |
serine/threonine kinase 9 cyclin-dependent kinase-like 5 |
| Locus: |
Xp22, 13 |
| Discovery year: |
1997-10-27 |
| GenBank acession: |
Y15057 |
| Entrez gene record: |
6792 |
| Pubmed identfication: |
9721213 16935860 |
| RefSeq identity: |
NM_003159 |
| Classification: |
Cyclin dependent kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000021214 |
| Locus Specific Databases: |
Mental Retardation database |