| Long name: |
FITC Conjugated, FARP2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
FARP2 |
| Specificity: |
This is a highly specific antibody against FARP2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human FARP2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Downregulation of the FARP2 gene has been implicated in autism, FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons, It exists as two alternatively spliced isoforms that are abundantly expressed in brain, Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, and testis as well as in embryonic hippocampal and cortical neurons, lung, one DH domain and two PH domains, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion, 545 amino acid protein that contains one FERM domain, FARP2 is a 1 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
KIAA0793 FIR PLEKHC3 FRG |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
FARP2 Conjugated |
| Short name: |
FITC Conjugated, FARP2 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, FARP2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16460 |
| Gene: |
FARP2 |
More about : FARP2 |
| Long gene name: |
ARH/RhoGEF and pleckstrin domain protein 2 , FERM |
| Synonyms gene name: |
FERM, RhoGEF and pleckstrin domain protein 2 |
| Locus: |
2q37, 3 |
| Discovery year: |
2002-11-29 |
| GenBank acession: |
AB018336 |
| Entrez gene record: |
9855 |
| Pubmed identfication: |
9872452 12351724 |
| Classification: |
Rho guanine nucleotide exchange factors Pleckstrin homology domain containing FERM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000151574 |