| Long name: |
Biotin Conjugated, ABLIM1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ABLIM1 |
| Specificity: |
This is a highly specific antibody against ABLIM1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human ABLIM1 |
| Gene ID number: |
3983 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, There are four known isoforms of ABLIM1, They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), also designated Limatin), and are localized on stress fibers, bind to F-Actin, brain and muscle tissue, elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors, thereby modulating transcription, thus identifying ABLIM1 as a candidate tumor suppressor gene, which conform to the LIM motif consensus sequence, The C |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
abLIM limatin |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
ABLIM1 Conjugated |
| Short name: |
Conjugated, ABLIM1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, ABLIM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
78 |
| Gene: |
ABLIM1 |
More about : ABLIM1 |
| Long gene name: |
actin binding LIM protein 1 |
| Synonyms gene: |
LIMAB1 ABLIM |
| Locus: |
10q25, 3 |
| Discovery year: |
1997-10-10 |
| GenBank acession: |
AF005654 |
| Entrez gene record: |
3983 |
| Pubmed identfication: |
9245787 |
| Classification: |
LIM domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000019088 |