| Long name: |
Biotin Conjugated, Thyroid Hormone Receptor beta Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
THRB1/Thyroid Hormone Receptor beta |
| Specificity: |
This is a highly specific antibody against THRB1/Thyroid Hormone Receptor beta |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Thyroid Hormone Receptor beta |
| Gene ID number: |
7068 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Defects in the receptor result in generalized thyroid hormone resistance (GTHR), GTHR is transmitted as an autosomal dominant trait, GTHR patients also have high levels of circulating thyroid hormones (T3-T4), It is composed of three domains: a modulating N-terminal domain, The disease is characterized by goiter, Thyroid hormone receptor b2 (TRb2) is a high affinity receptor for triiodothyronine which belongs to the nuclear hormone receptor family and the NR1 subfamily, a DNA-binding domain and a C-terminal steroid-binding domain, abnormal growth and bone maturation, abnormal mental functions, but an autosomal recessive form also exists, increased susceptibility to infections, tachycardia and deafness, with normal or slightly elevated thyroid stimulating hormone, Thyroid hormone receptors (TRs) are ligand-dependent transcription factors that mediate the biological activities of thyroid hormone (T3) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
Avian erythroblastic leukemia viral v erb a oncogene homolog 2, C ERBA 2, C ERBA BETA, ERBA 2, ERBA BETA, ERBA2, Erythroblastic leukemia viral v erb a oncogene homolog 2 avian, GRTH, MGC126109, MGC126110, NR1A2, Nuclear receptor subfamily 1 group A member 2, Oncogene ERBA2, PRTH, THB_HUMAN, THR 1, THR1, THRB, THRB 1, THRB 2, THRB1, THRB2, Thyroid hormone nuclear receptor beta variant 1, Thyroid hormone receptor, Thyroid hormone receptor beta, Thyroid hormone receptor beta 1, Thyroid hormone receptor beta 2, avian, beta erythroblastic leukemia viral v erb a oncogene homolog 2, c-erbA-2, c-erbA-beta, generalized resistance to thyroid hormone, Thyroid Hormone Receptor beta |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Description: |
FSH comprise the , Human recombinant LHRG and GHRH are produced in E, The glands that secrete Luteinizing hormones LHRG and LH, The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine , coli or in yeast cells, Hormone releasing factors and releasing hormones are , endocrine signaling system, glands , in , intracrine signaling) or nearby cells (paracrine signaling), multicellular organisms, or , produced by , signaling molecules |
| Gene target: |
Thyroid Hormone Receptor beta Conjugated |
| Short name: |
Conjugated, Thyroid Hormone Receptor beta Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Thyroid Hormone Receptor b (Antibody to) |
| Alternative technique: |
antibodies |