| Long name: |
DUOX1 Primary Polyclonal Antibody |
| Also known as: |
DUOX1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DUOX1 |
| Specificity: |
This is a highly specific antibody against DUOX1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DUOX1 |
| Gene ID number: |
53905 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
DUOX1, DUOX1 generates hydrogen peroxide, DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa, a homolog of glycoprotein p91Phox, as well as thyroid, is expressed in airway epithelium and generates reactive oxygen species (ROS), is widely expressed in fetal tissues, trachea and bronchium, which also plays a role in mucin expression, which is crucial for thyroid peroxidase and lactoperoxidase, Dual oxidase 1 (DUOX1) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DUOX1, DUOX1_HUMAN, Dual oxidase 1 precursor, EC 1, EC 1, Flavoprotein NADPH oxidase, LNOX1, Large NOX 1, Long NOX 1, MGC138840, MGC138841, NADPH thyroid oxidase 1, NOXEF1, Nicotinamide adenine dinucleotide phosphate oxidase, THOX1, Thyroid oxidase 1, 1, 1, 3, 6, 11, Dual oxidase 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DUOX1 |
| Short name: |
DUOX1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
dual oxidase 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DUOX1 and IDBG-10154 and ENSG00000137857 and 53905, DUOX1 and IDBG-646697 and ENSBTAG00000016246 and 510409, Duox1 and IDBG-202931 and ENSMUSG00000033268 and 99439, NADP binding, Plasma membranes, this GO :0004601 and peroxidase activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006590 and thyroid hormone generation and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016174 and NAD(P)H oxidase activity and molecular function this GO :0016324 and apical plasma membrane and cellular component this GO :0016491 and oxidoreductase activity and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0020037 and heme binding and molecular function this GO :0042335 and cuticle development and biological process this GO :0042446 and hormone biosynthetic process and biological process this GO :0042554 and superoxide anion generation and biological process this GO :0042744 and hydrogen peroxide catabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0050661 and NADP binding and molecular function this GO :0050665 and hydrogen peroxide biosynthetic process and biological process this GO :0051591 and response to cAMP and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process, this GO :0004601 : peroxidase activity, this GO :0004601 : peroxidase activity and also this GO :0005509 : calcium ion binding and also this GO :0005515 : protein binding and also this GO :0016174 : NAD(P)H oxidase activity and also this GO :0016491 : oxidoreductase activity and also this GO :0020037 : heme binding and also this GO :0050661 : NADP binding, this GO :0005509 : calcium ion binding, this GO :0005515 : protein binding, this GO :0016174 : NAD(P)H oxidase activity, this GO :0016491 : oxidoreductase activity, this GO :0020037 : heme binding, this GO :0050661 : NADP binding, dual oxidase 1 |
| Identity: |
3062 |
| Gene: |
DUOX1 |
More about : DUOX1 |
| Long gene name: |
dual oxidase 1 |
| Synonyms: |
NOXEF1 THOX1 LNOX1 |
| Synonyms name: |
NADPH thyroid oxidase 1 flavoprotein NADPH oxidase nicotinamide adenine dinucleotide phosphate oxidase |
| Locus: |
15q21, 1 |
| Discovery year: |
2000-05-30 |
| GenBank acession: |
AF213465 |
| Entrez gene record: |
53905 |
| Pubmed identfication: |
10806195 |
| RefSeq identity: |
NM_017434 |
| Classification: |
EF-hand domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000171987 |