| Long name: |
Biotin Conjugated, CRSP9 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
CRSP9 |
| Specificity: |
This is a highly specific antibody against CRSP9 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human CRSP9 |
| Gene ID number: |
9443 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Additionally, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2, Med6 and Med7, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6), SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, These complexes include the SMCC (SRB and MED protein cofactor complex), and including the human proteins Srb7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4), in turn, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, 3), 5), In mammalian cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CRSP33 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CRSP9 Conjugated |
| Short name: |
Conjugated, CRSP9 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, CRSP9 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
2378 |
| Gene: |
MED7 |
More about : MED7 |
| Long gene name: |
mediator complex subunit 7 |
| Synonyms gene: |
CRSP9 |
| Synonyms gene name: |
33kDa , cofactor required for Sp1 transcriptional activation, subunit 9 |
| Locus: |
5q33, 3 |
| Discovery year: |
1999-07-21 |
| GenBank acession: |
AF104251 |
| Entrez gene record: |
9443 |
| Pubmed identfication: |
9989412 |
| RefSeq identity: |
NM_004270 |
| Classification: |
Mediator complex |
| Havana BLAST/BLAT: |
OTTHUMG00000130243 |