| Long name: |
NMUR2/GPR-FM4 Primary Polyclonal Antibody |
| Also known as: |
NMUR2/GPR-FM4 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NMUR2/GPR-FM4 |
| Specificity: |
This is a highly specific antibody against NMUR2/GPR-FM4 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NMUR2 |
| Gene ID number: |
56923 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Both NMUR1 and NMUR2 act as receptors for the neuromedin U neuropeptide, It is widely expressed in gastrointestinal systems and central nervous system (CNS), It may also be detected in testis but has low levels of expression in peripheral tissues, Itâ, NMUR1 is detected in peripheral organs, NMUR2 is predominantly detected in central nervous system with highest levels detected in medulla oblongata, Neuromedin U receptors 1 and 2 (NMUR1 and NMUR2) are multi-pass membrane proteins that belong to the G-protein coupled receptor 1 family of proteins, Peripheral activities of neuromedin U include smooth muscle stimulation, but the protein has been detected in cerebellum, dorsal root ganglia and spinal cord, hippocampus, ion transport alterations in the gut and the regulation of local blood flow and adrenocortical function, particularly in urogenital and gastrointestinal systems, spinal cord and thalamus, with highest levels in testis, &euro, &trade, Neuromedin U is a neuropeptide with high activity on smooth muscle, s expression in CNS is low |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
G protein coupled receptor FM 4, G protein coupled receptor TGR 1, G-protein coupled receptor FM-4, G-protein coupled receptor TGR-1, NMU R2, NMU-R2, NMU2R, NMUR2, NMUR2_HUMAN, Neuromedin U receptor 2, Neuromedin-U receptor 2, TGR1, FM4 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NMUR2/GPR-FM4 |
| Short name: |
NMUR2/GPR-FM4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NMUR2/GPR-FM4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16454 |
| Gene: |
NMUR2 |
More about : NMUR2 |
| Long gene name: |
neuromedin U receptor 2 |
| Synonyms gene: |
NMU2R |
| Locus: |
5q33, 1 |
| Discovery year: |
2001-08-24 |
| GenBank acession: |
AF242874 |
| Entrez gene record: |
56923 |
| Pubmed identfication: |
8940772 10894543 |
| RefSeq identity: |
NM_020167 |
| Classification: |
Neuromedin U receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000130131 |