| Long name: |
AASS/LKRSDH Primary Polyclonal Antibody |
| Also known as: |
AASS/LKRSDH PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
AASS/LKRSDH |
| Specificity: |
This is a highly specific antibody against AASS/LKRSDH |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LKRSDH |
| Gene ID number: |
10157 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
AASS acts as a bifunctional enzyme containing the lysine alpha-ketoglutarate reductase (LKR) and saccharopine dehydrogenase activities that catalyzes the first two steps in lysine degradation, However, It is widely expressed with highest expression in liver and transcription of the AASS gene is induced upon starvation, Mutations in the gene encoding AASS result in various forms familial hyperlysinemias (FH), also designated lysine ketoglutarate reductase (LKR) or saccharopine dehydrogenase (SDH), and variable saccharopinuria, autosomal recessive disorders characterized by hyperlysinemia, is a 926 amino acid protein that exists as a homodimer in the mitochondria, lysinuria, no adverse mental or physical effects have been found in patients with hyperlysinemia, Alpha-aminoadipic semialdehyde synthase (AASS) |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AASS_HUMAN, LKR/SDH, LKRSDH, LORSDH, Lysine ketoglutarate reductase, Saccharopine dehydrogenase, Alpha aminoadipic semialdehyde synthase mitochondrial |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
AASS/LKRSDH |
| Short name: |
AASS/LKRSDH Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
AASS/LKRSDH (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17366 |
| Gene: |
AASS |
More about : AASS |
| Long gene name: |
aminoadipate-semialdehyde synthase |
| Synonyms: |
LORSDH LKRSDH |
| Locus: |
7q31, 32 |
| Discovery year: |
2002-01-09 |
| GenBank acession: |
AF229180 |
| Entrez gene record: |
10157 |
| Pubmed identfication: |
10775527 |
| RefSeq identity: |
NM_005763 |
| Havana BLAST/BLAT: |
OTTHUMG00000157058 |