| Long name: |
A4GNT Primary Polyclonal Antibody |
| Also known as: |
A4GNT PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
A4GNT |
| Specificity: |
This is a highly specific antibody against A4GNT |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human A4GNT |
| Gene ID number: |
51146 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alpha4Gn-T acts as the key enzyme for the formation of the unique glycan GlcNAcalpha1-4Galbeta1-R, Alpha4Gn-T and Mucin 6 expression is upregulated in the gastric mucosa of H, Alpha4Gn-T is a single-pass type II membrane protein associated with the Golgi apparatus and contains the conserved DXD motif involved in catalytic activity, Alpha4Gn-T is not expressed in peripheral blood cells, It is expressed in stomach and pancreas, and most efficiently transfers N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans, as well as in gastric cancer cells, making it a useful biomarker for pancreatic cancer, pylori infection, which suggest the involvement of ?Gn-T in defense against H, 4-N-acetylflucosaminyltransferase (Alpha4Gn-T) mediates the biosynthesis of mucin type glycoprotein (O-glycan), Alpha 1, pylori infected patients |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
A4GCT_HUMAN, A4GNT, Alpha 1 4 N acetylglucosaminyltransferase, Alpha-1, Alpha4GnT, EC 2, MGC149493, 1, 4, 4-N-acetylglucosaminyltransferase |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
A4GNT |
| Short name: |
A4GNT Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
A4GNT (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
17968 |
| Gene: |
A4GNT |
More about : A4GNT |
| Long gene name: |
alpha-1, 4-N-acetylglucosaminyltransferase |
| Synonyms: |
alpha4GnT |
| Locus: |
3q22, 3 |
| Discovery year: |
2004-07-12 |
| GenBank acession: |
AF141315 |
| Entrez gene record: |
51146 |
| Pubmed identfication: |
10430883 |
| RefSeq identity: |
NM_016161 |
| Classification: |
Alpha 1, 4-glycosyltransferases |
| Havana BLAST/BLAT: |
OTTHUMG00000159820 |