| Long name: |
FITC Conjugated, SV2B Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SV2B |
| Specificity: |
This is a highly specific antibody against SV2B |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human SV2B |
| Gene ID number: |
9899 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
SV2 proteins are abundant, SV2 proteins are differentially expressed in the brain and are present on all synaptic vesicles, SV2A and SV2B, SV2A and SV2B are funtionally redundant and are required for maintaining normal brain function in vertebrates, SV2A and SV2B mediate synaptic transmission by regulating cytoplasmic Ca2+ levels in the nerve terminal during repetitive stimulation, SV2A is abundantly expressed in the subcortex, SV2B displays a more restricted pattern of expression in that it is only present on a small subset of synapses in the hippocampus and cortex, SV2C, and also in most neuroendocrine secretory granules, and one minor isoform, hydrophobic, independent of transmitter type, membrane glycoproteins that are expressed as two major isoforms, specifically in the synaptic vesicles of all presynaptic nerve terminals, In all vertebrates |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
KIAA0735 HsT19680 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SV2B Conjugated |
| Short name: |
FITC Conjugated, SV2B Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SV2B (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16874 |
| Gene: |
SV2B |
More about : SV2B |
| Long gene name: |
synaptic vesicle glycoprotein 2B |
| Locus: |
15q26, 1 |
| Discovery year: |
2003-02-24 |
| GenBank acession: |
AB018278 |
| Entrez gene record: |
9899 |
| Pubmed identfication: |
9872452 7681585 |
| RefSeq identity: |
NM_014848 |
| Havana BLAST/BLAT: |
OTTHUMG00000149833 |