| Long name: |
RIMS3 Primary Polyclonal Antibody |
| Also known as: |
RIMS3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RIMS3 |
| Specificity: |
This is a highly specific antibody against RIMS3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RIMS3 |
| Gene ID number: |
9783 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Localized to the synapse and to cell junctions, Rim2, Rim3, Rim3, Rim3 and Rim4) are multidomain adaptors that regulate Rab 3 activity and sub-sequent neurotransmitter release, Rim3 contains one C2 domain and is thought to play an important role in the regulation of synaptic membrane exocytosis, The Rim (Rab 3 interacting molecule) family of proteins (Rim1, a neural/neuroendocrine-specific member of the Rab family, a protein that may be phosphorylated upon DNA damage, also known as RIMS3 (regulating synaptic membrane exocytosis 3) or NIM3, controlling the recruitment and pooling of secretory vesicles at the plasma membrane, is a 308 amino acid member of the Rim family, is expressed throughout the body with highest levels present in brain tissue, is involved in Ca2+-regulated exocytosis and functions in an inhibitory capacity, Rab 3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
NIM3, RIM 3, RIM3, RIM3 gamma, RIMS 3, RIMS-3, RIMS3, RIMS3_HUMAN, Rab 3 interacting molecule 3, Regulating synaptic membrane exocytosis 3, Regulating synaptic membrane exocytosis protein 3, NIM 3 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RIMS3 |
| Short name: |
RIMS3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
regulating synaptic membrane exocytosis 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Cell surfaces, NIM3 and RIM3, RIMS3 and IDBG-640710 and ENSBTAG00000018726 and 519929, RIMS3 and IDBG-96977 and ENSG00000117016 and 9783, Rims3 and IDBG-184010 and ENSMUSG00000032890 and 242662, ion channel binding, this GO :0005515 and protein binding and molecular function this GO :0006836 and neurotransmitter transport and biological process this GO :0006887 and exocytosis and biological process this GO :0030054 and cell junction and cellular component this GO :0042391 and regulation of membrane potential and biological process this GO :0044325 and ion channel binding and molecular function this GO :0045202 and synapse and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0044325 : ion channel binding, this GO :0044325 : ion channel binding, regulating synaptic membrane exocytosis 3 |
| Identity: |
21292 |
| Gene: |
RIMS3 |
More about : RIMS3 |
| Long gene name: |
regulating synaptic membrane exocytosis 3 |
| Synonyms: |
RIM3 NIM3 |
| Locus: |
1p34, 2 |
| Discovery year: |
2003-06-19 |
| GenBank acession: |
BC003103 |
| Entrez gene record: |
9783 |
| Pubmed identfication: |
12620390 10748113 |
| RefSeq identity: |
NM_014747 |
| Classification: |
Regulating synaptic membrane exocytosis family |
| Havana BLAST/BLAT: |
OTTHUMG00000007453 |