| Long name: |
Biotin Conjugated, RIC8A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RIC8A |
| Specificity: |
This is a highly specific antibody against RIC8A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human RIC8A |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Arf, Functioning as a guanine nucleotide exchange factor, G?q and G?o, RIC-8A (resistance to inhibitors of cholinesterase 8 homolog A), RIC-8A binds to GDP-associated substrates and exchanges bound GDP for free GTP, RIC-8A is expressed as three isoforms due to alternative splicing events, RIC-8A plays a role in regulating mitotic movement and may be involved in receptor-mediated ERK activation, Rab, Rap and Ran subfamilies, Rho/Rac, Sar, The Ras superfamily of GTPases function as regulated switches that toggle between a biologically active GTP-bound and an inactive GDP-bound form, This activation is catalyzed by guanine nucleotide exchange factors (GEFs), Via its ability to stimulate protein function, all of which control multiple aspects of cell function, also known as RIC8 or Synembryn-A, including G?i-1, including cytoskeletal rearrangement, is a 530 amino acid cytoplasmic protein that can activate several G-alpha proteins, nuclear signaling and cell growth, The Ras superfamily of GTPases can be subdivided into the Ras |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
synembryn synembryn-A |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RIC8A Conjugated |
| Short name: |
Conjugated, RIC8A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, RIC8A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29550 |
| Gene: |
RIC8A |
More about : RIC8A |
| Long gene name: |
RIC8 guanine nucleotide exchange factor A |
| Synonyms gene name: |
elegans) , resistance to inhibitors of cholinesterase 8 homolog A (C |
| Locus: |
11p15, 5 |
| Discovery year: |
2005-08-17 |
| GenBank acession: |
AK022870 |
| Entrez gene record: |
60626 |
| Pubmed identfication: |
10985349 11230166 |
| RefSeq identity: |
NM_021932 |
| Havana BLAST/BLAT: |
OTTHUMG00000119069 |