| Long name: |
ALEXA FLUOR 350 Conjugated, MCM4/CDC21 Polyclonal Antibody |
| Also known as: |
Anti-MCM4/CDC21 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MCM4/CDC21 |
| Specificity: |
This is a highly specific antibody against MCM4/CDC21 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MCM4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Cleavage of MCM3, Expression of MCM proteins increases during cell growth, MCM proteins are regulated by E2F transcription factors, MCM2/MCM4 complexes function as substrates for Cdc2/cyclin B in vitro, MCM3, MCM4 (Cdc21), MCM5 (Cdc46), MCM6 (Mis5) and MCM7 (Cdc47), The MCM proteins each contain an ATP-binding motif, and by protein kinases, are regulators of DNA replication that act to ensure replication occurs only once in the cell cycle, including MCM2, peaking at G1 to S phase, results in the inactivation of the MCM complex (composed of at least MCM proteins 2-6) during apoptosis, which can be prevented by caspase inhibitors, which induce MCM expression, which interact with MCM proteins to maintain the postreplicative state of the cell, which is predicted to mediate ATP-dependent opening of double-stranded DNA, The mini-chromosome maintenance (MCM) family of proteins |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Synonyms: |
CDC54 hCdc21 P1-Cdc21 MGC33310 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
MCM4/CDC21 |
| Short name: |
MCM4/CDC21 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, MCM4/CDC21 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6947 |
| Gene: |
MCM4 |
More about : MCM4 |
| Long gene name: |
minichromosome maintenance complex component 4 |
| Synonyms gene: |
CDC21 |
| Synonyms gene name: |
MCM4 minichromosome maintenance deficient 4 (S, cerevisiae) |
| Locus: |
8q11, 21 |
| Discovery year: |
1994-12-13 |
| Entrez gene record: |
4173 |
| Pubmed identfication: |
7601140 |
| RefSeq identity: |
NM_005914 |
| Classification: |
MCM family |
| Havana BLAST/BLAT: |
OTTHUMG00000164205 |