| Long name: |
FITC Conjugated, SNIP1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SNIP1 |
| Specificity: |
This is a highly specific antibody against SNIP1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human SNIP1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Effects of TGF-Beta family ligands are mediated by Smad proteins, SNIP1 is also thought to induce expression of Cyclin D1 to promote cellular proliferation, SNIP1 is ubiquitously expressed with high expression in heart and skeletal muscle, SNIP1 potently inhibits the activity of NF-kappa B, The Smad nuclear interacting protein (SNIP1) contains a forkhead-associated (FHA) domain and acts as a nuclear inhibitor of CBP/p300, by competing for the binding site, which binds the C/H1 domain of CBP/p300, Members of the transforming growth factor-beta (TGF-Beta) superfamily play critical roles in controlling cell growth and differentiation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SNIP1 Conjugated |
| Short name: |
FITC Conjugated, SNIP1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SNIP1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
30587 |
| Gene: |
SNIP1 |
More about : SNIP1 |
| Long gene name: |
Smad nuclear interacting protein 1 |
| Locus: |
1p34, 3 |
| Discovery year: |
2005-06-06 |
| Entrez gene record: |
79753 |
| Pubmed identfication: |
10887155 15378006 |
| RefSeq identity: |
NM_024700 |
| Havana BLAST/BLAT: |
OTTHUMG00000004225 |