| Long name: |
ALEXA FLUOR 350 Conjugated, Rab17 Polyclonal Antibody |
| Also known as: |
Anti-Rab17 PAb ALEXA FLUOR 350 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
350, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Rab17 |
| Specificity: |
This is a highly specific antibody against Rab17 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Rab17 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells, It is specifically expressed in epithelial cells and is upregulated during cell polarization, Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking, Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis, The function of Rab17 remains unclear, siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery, Rab17 belongs to the Rab family of small Ras-like GTPases |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
343nm/442nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 350, Alexa Fluor |
| Gene target: |
Rab17 |
| Short name: |
Rab17 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 350 |
| Alternative name: |
ALEXA FLUOR 350, Rab17 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
16523 |
| Gene: |
RAB17 |
More about : RAB17 |
| Long gene name: |
RAB17, member RAS oncogene family |
| Locus: |
2q37, 3 |
| Discovery year: |
2001-09-14 |
| GenBank acession: |
AK022600 |
| Entrez gene record: |
64284 |
| Pubmed identfication: |
9624171 |
| Classification: |
RAB, member RAS oncogene GTPases |
| Havana BLAST/BLAT: |
OTTHUMG00000133299 |