| Long name: |
FITC Conjugated, RECQL5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
RECQL5 |
| Specificity: |
This is a highly specific antibody against RECQL5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human RECQL5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
It has been shown in mouse embryonic stem (ES) cells that mutations in the Recql5 genes result in a significant increase in the frequency of sister chromatid exchange (SCE), RecQL5 is one of five known RecQ homologues in humans, The exact role of ReqL5 is unclear, There are three different RecQL5 isoforms - alpha, WRN and RecQ4)are associated with autosomal recessive disorders that involve genomic instability and a predisposition to cancer, and defects in three of these (BLM, beta and gamma, produced by alternative splicing, whereas deleting Recql5 lead to an even higher frequency of SCE, RecQ helicases are implicated in DNA recombination and repair helicases and are critical in genome maintenance |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
RecQ5 FLJ90603 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RECQL5 Conjugated |
| Short name: |
FITC Conjugated, RECQL5 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, RECQL5 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9950 |
| Gene: |
RECQL5 |
More about : RECQL5 |
| Long gene name: |
RecQ like helicase 5 |
| Synonyms name: |
RecQ protein 5 |
| Locus: |
17q25 |
| Discovery year: |
1999-05-06 |
| GenBank acession: |
AB006533 |
| Entrez gene record: |
9400 |
| Pubmed identfication: |
9878247 |
| RefSeq identity: |
NM_004259 |
| Classification: |
RecQ like helicases |
| Havana BLAST/BLAT: |
OTTHUMG00000179795 |