| Long name: |
ALEXA FLUOR 488 Conjugated, OTUB1 Polyclonal Antibody |
| Also known as: |
Anti-OTUB1 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
OTUB1 |
| Specificity: |
This is a highly specific antibody against OTUB1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OTUB1 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Due to its interaction with GRAIL, Expressed as two isoforms (one of which is present throughout the body and the other of which is present only in lymphoid tissues), OTUB1 functions as a hydrolase that can remove ubiquitin residues from target proteins, OTUB1 interacts with GRAIL and, OTUB1 is an important regulator of immune responses in secondary lymphoid organs, a phenomenon that occurs when T-cells are rendered unresponsive to their cognate antigens, plays a role in the regulation and the induction of T-cell anergy, thereby preventing protein degradation and playing an important role in protein turnover, via this interaction, OTUB1 is a 271 amino acid protein that contains one OTU (ovarian tumor) domain and belongs to the OTU family of predicted cysteine proteases |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
FLJ20113 FLJ40710 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the OTUB1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
OTUB1 |
| Short name: |
OTUB1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, OTUB1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
23077 |
| Gene: |
OTUB1 |
More about : OTUB1 |
| Long gene name: |
OTU deubiquitinase, ubiquitin aldehyde binding 1 |
| Synonyms gene name: |
OTU domain, ubiquitin aldehyde binding 1 |
| Locus: |
11q13, 1 |
| Discovery year: |
2003-12-12 |
| GenBank acession: |
AY177200 |
| Entrez gene record: |
55611 |
| Pubmed identfication: |
12704427 19383985 |
| RefSeq identity: |
NM_017670 |
| Classification: |
OTU domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000167786 |