| Long name: |
ALEXA FLUOR 488 Conjugated, SH3TC2 Polyclonal Antibody |
| Also known as: |
Anti-SH3TC2 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SH3TC2 |
| Specificity: |
This is a highly specific antibody against SH3TC2 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SH3TC2 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also, Charcot-Marie-Tooth disease type 4C (CMT4C) is a more severe neuropathy caused by homozygous or compound heterozygous mutation in the SH3TC2 gene, Existing as four alternatively spliced isoforms and containing 18 exons, Mild mononeuropathy of the median nerve (MNMN) is caused by heterozygous mutation in the SH3TC2 gene, The SH3TC2 gene encodes a protein expressed in Schwann cells of peripheral nerves, The SH3TC2 protein is expressed in adult heart, and brain as well as in fetal brain and liver, and localized to the plasma membrane and to the perinuclear endocytic recycling compartment, and maps to human chromosome 5q32, chicken and zebrafish, cow, dog, mouse, rat, spinal cord, suggesting a possible function in myelination and/or in regions of axoglial interactions, testis, the SH3TC2 gene is conserved in chimpanzee, 288 amino acid protein that contains one SH3 domain and eight TPR repeats, SH3TC2 (SH3 domain and tetratricopeptide repeats 2) is a 1 |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
KIAA1985 CMT4C |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the SH3TC2 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
SH3TC2 |
| Short name: |
SH3TC2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, SH3TC2 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
29427 |
| Gene: |
SH3TC2 |
More about : SH3TC2 |
| Long gene name: |
SH3 domain and tetratricopeptide repeats 2 |
| Locus: |
5q32 |
| Discovery year: |
2004-12-15 |
| GenBank acession: |
AK127248 |
| Entrez gene record: |
79628 |
| Pubmed identfication: |
14574644 |
| RefSeq identity: |
NM_024577 |
| Classification: |
Tetratricopeptide repeat domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000129930 |
| Locus Specific Databases: |
Inherited Peripheral Neuropathies Mutation Database LRG_269 |