| Long name: |
FITC Conjugated, LRRTM1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LRRTM1 |
| Specificity: |
This is a highly specific antibody against LRRTM1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human LRRTM1 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
All LRR repeats contain a variable segment and a highly conserved segment, Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders, Expressed predominately in forebrain tissue, Human LRRTM1 shares 96% amino acid identity with its mouse counterpart, LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats, LRRTM1 is thought to be involved in the development of forebrain structures, allowing it to accommodate several leucine residues within a tightly packed core, as well as neuronal differentiation and connectivity, specifically by influencing axon trafficking, suggesting a conserved role between species, the latter of which accounts for 11 or 12 residues of the entire LRR motif, The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
FLJ32082 |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
LRRTM1 Conjugated |
| Short name: |
FITC Conjugated, LRRTM1 Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, LRRTM1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
19408 |
| Gene: |
LRRTM1 |
More about : LRRTM1 |
| Long gene name: |
leucine rich repeat transmembrane neuronal 1 |
| Locus: |
2p12 |
| Discovery year: |
2004-06-22 |
| GenBank acession: |
AY358310 |
| Entrez gene record: |
347730 |
| Pubmed identfication: |
12676565 |
| RefSeq identity: |
NM_178839 |
| Havana BLAST/BLAT: |
OTTHUMG00000130021 |