| Long name: |
ALEXA FLUOR 647 Conjugated, C9a/C9 Polyclonal Antibody |
| Also known as: |
Anti-C9a/C9 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
C9a/C9 |
| Specificity: |
This is a highly specific antibody against C9a/C9 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Complement component C9a |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
C6, C7 and C8, C9 binds to the membrane associated C5b-8 protein, C9 is a part of the membrane attack complex (MAC), Molecules can then diffuse freely through this transmembrane channel, The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, These complement proteins bind to the outer surface of the plasma membrane of the invading cell, These polymerized C9 molecules form a ring structure in the membrane, an important component of the immune system, causing cell lysis and destruction of the invading bacterial cell, which leads to the circular polymerization of 12-18 C9 molecules, C9 is a plasma protein synthesized in the liver and monocytes consisting of a single polypeptide chain |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
C9, C9 deficiency, C9 deficiency with dermatomyositis, CO9_HUMAN, Complement component 9, Complement component 9 deficiency, Complement component C9a, Complement component C9a, C9a |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the C9a/C9 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
C9a/C9 |
| Short name: |
C9a/C9 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, C9a/complement component 9 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ARMD15 and C9D, C9 and IDBG-128081 and ENSMUSG00000022149 and 12279, C9 and IDBG-17892 and ENSG00000113600 and 735, C9 and IDBG-629942 and ENSBTAG00000016149 and 526766, Extracellular, alternative pathway and biological process this GO :0006958 and complement activation, classical pathway and biological process this GO :0019836 and hemolysis by symbiont of host erythrocytes and biological process this GO :0030449 and regulation of complement activation and biological process this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072562 and blood microparticle and cellular component, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005579 and membrane attack complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006957 and complement activation, this GO :0005515 : protein binding, this GO :0005515 : protein binding, complement component 9 |