| Long name: |
Biotin Conjugated, PCDHB4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
PCDHB4 |
| Specificity: |
This is a highly specific antibody against PCDHB4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human PCDHB4 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
As a result, PCDHB4 (Protocadherin beta-4) is a 795 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster, PCDHB4 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain, There are three protocadherin gene clusters, Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, all of which contain multiple tandemly arranged genes, beta and gamma, designated alpha, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein, members of the beta cluster (such as PCDHB4) do not use constant-region exons to produce mRNAs, Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
PCDH-BETA4 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PCDHB4 Conjugated |
| Short name: |
Conjugated, PCDHB4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, protocadherin b 4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
PCDHB4 and IDBG-49897 and ENSG00000081818 and 56131, PCDHB4 and IDBG-648649 and ENSBTAG00000045603 and 786553, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007399 and nervous system development and biological process this GO :0007416 and synapse assembly and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016339 and calcium-dependent cell-cell adhesion and biological process this GO :0045111 and intermediate filament cytoskeleton and cellular component, this GO :0005509 : calcium ion binding, this GO :0005509 : calcium ion binding, protocadherin beta 4 |
| Identity: |
8689 |
| Gene: |
PCDHB4 |
More about : PCDHB4 |
| Long gene name: |
protocadherin beta 4 |
| Locus: |
5q31, 3 |
| Discovery year: |
2000-06-28 |
| GenBank acession: |
AF152497 |
| Entrez gene record: |
56131 |
| Pubmed identfication: |
10380929 |
| RefSeq identity: |
NM_018938 |
| Classification: |
Clustered protocadherins |
| Havana BLAST/BLAT: |
OTTHUMG00000129617 |