| Long name: |
Biotin Conjugated, MPZL2/EVA1 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
MPZL2/EVA1 |
| Specificity: |
This is a highly specific antibody against MPZL2/EVA1 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Extracellular |
| Source: |
KLH conjugated synthetic peptide derived from human MPZL2/EVA1 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression, It is highly homologous to the myelin protein zero and, Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis, Jul 2008], The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain, This gene is expressed in the thymus and in several epithelial structures early in embryogenesis, Two transcript variants encoding the same protein have been found for this gene, [provided by RefSeq, a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton, Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
EVA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MPZL2/EVA1 Conjugated |
| Short name: |
Conjugated, MPZL2/EVA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, myelin protein zero-like 2/EVA1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
EVA and EVA1, MPZL2 and IDBG-631254 and ENSBTAG00000033510 and 540423, MPZL2 and IDBG-73587 and ENSG00000149573 and 10205, Mpzl2 and IDBG-159117 and ENSMUSG00000032092 and 14012, Plasma membranes, protein binding, this GO :0005515 and protein binding and molecular function this GO :0005856 and cytoskeleton and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0033077 and T cell differentiation in thymus and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding, myelin protein zero-like 2 |
| Identity: |
3496 |
| Gene: |
MPZL2 |
More about : MPZL2 |
| Long gene name: |
myelin protein zero like 2 |
| Synonyms gene: |
EVA1 |
| Synonyms gene name: |
epithelial V-like antigen 1 |
| Locus: |
11q24 |
| Discovery year: |
1999-11-22 |
| GenBank acession: |
AF275945 |
| Entrez gene record: |
10205 |
| Pubmed identfication: |
9585423 |
| RefSeq identity: |
NM_005797 |
| Classification: |
V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166967 |