| Long name: |
BFSP2/Phakinin Primary Polyclonal Antibody |
| Also known as: |
BFSP2/Phakinin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
BFSP2/Phakinin |
| Specificity: |
This is a highly specific antibody against BFSP2/Phakinin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BFSP2/Phakinin |
| Gene ID number: |
3921 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
IFs are cytoskeletal structures that typically contain a head, Mutations in the gene encoding Phakinin can result in lens cataract, Phakinin completely lacks the C-terminal tail domain thus contributing to the unique structure of the beaded filament that is specific to the lens, Phakinin copolymerizes with Filensin, Phakinin is also capable of self-assembling into filament-like structures that form thicker bundles, Phakinin is required for the assembly of beaded filaments and cytoskeletal networks that are important for the long-term maintenance of optical properties and transparency of the lens, Unlike most IFs, another IF protein, rod and tail domain, to form the 10-nm filamentous structures of the beaded filaments, Phakinin is a membrane-associated and cytoskeletal intermediate filament (IF) protein specific to the eye lens |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
49 kD, BFSP2, BFSP2_HUMAN, Beaded filament protein CP49, Beaded filament structural protein 2, Beaded filament structural protein 2, Bfps2, CP47, CP49, Cytoskeletal protein, LL-L, Lens fiber cell beaded filament protein CP 47, Lens fiber cell beaded filament protein CP 49, PHAKOSIN, Phakinin, phakinin, 49 kDa cytoskeletal protein, Lens intermediate filament-like light |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
BFSP2/Phakinin |
| Short name: |
BFSP2/Phakinin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
BFSP2/Phakinin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1041 |
| Gene: |
BFSP2 |
More about : BFSP2 |
| Long gene name: |
beaded filament structural protein 2 |
| Synonyms gene name: |
beaded filament structural protein 2, phakinin |
| Synonyms: |
CP47 CP49 LIFL-L phakinin |
| Locus: |
3q22, 1 |
| Discovery year: |
1999-04-14 |
| GenBank acession: |
U48224 |
| Entrez gene record: |
8419 |
| Classification: |
Beaded filament structural proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000159719 |
| Locus Specific Databases: |
Human Intermediate Filament Mutation Database |