| Long name: |
Biotin Conjugated, DHRS2 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
DHRS2 |
| Specificity: |
This is a highly specific antibody against DHRS2 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
125-150/258 |
| Subcellular location: |
Mitochondrion, Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human DHRS2 |
| Gene ID number: |
10202 |
| Swiss Prot: |
Q13268 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
2, Attenuates MDM2-mediated p53/TP53 degradation, No reductase activity is displayed in vitro with steroids, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21, retinoids and sugars as substrates, 2-propanedione as substrates, 3-Heptanedione and 1-Phenyl-1, 4-Hexanedione, Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
HEP27 SDR25C1 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DHRS2 Conjugated |
| Short name: |
DHRS2 Antibody Conjugated |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, dehydrogenase/reductase (SDR family) member 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DHRS2 and IDBG-3407 and ENSG00000100867 and 10202, Dhrs2 and IDBG-163262 and ENSMUSG00000022209 and 71412, HEP27 and SDR25C1, nuclei, oxidoreductase activity, this GO :0004090 and carbonyl reductase (NADPH) activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0008152 and metabolic process and biological process this GO :0008207 and C21-steroid hormone metabolic process and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009636 and response to toxic substance and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0034599 and cellular response to oxidative stress and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004090 : carbonyl reductase (NADPH) activity, this GO :0004090 : carbonyl reductase (NADPH) activity and also this GO :0016491 : oxidoreductase activity, this GO :0016491 : oxidoreductase activity, dehydrogenase/reductase (SDR family) member 2 |
| Identity: |
18349 |
| Gene: |
DHRS2 |
More about : DHRS2 |
| Long gene name: |
dehydrogenase/reductase 2 |
| Synonyms gene name: |
dehydrogenase/reductase (SDR family) member 2 |
| Synonyms name: |
member 1 , short chain dehydrogenase/reductase family 25C |
| Locus: |
14q11, 2 |
| Discovery year: |
2002-04-26 |
| Entrez gene record: |
10202 |
| Pubmed identfication: |
7556196 11944995 16685466 19027726 |
| RefSeq identity: |
NM_182908 |
| Classification: |
Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000028771 |