| Long name: |
DHRS2 Primary Polyclonal Antibody |
| Also known as: |
DHRS2 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
DHRS2 |
| Specificity: |
This is a highly specific antibody against DHRS2 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
125-150/258 |
| Subcellular location: |
Mitochondrion, Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human DHRS2 |
| Gene ID number: |
10202 |
| Swiss Prot: |
Q13268 |
| Tested Applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
2, Attenuates MDM2-mediated p53/TP53 degradation, No reductase activity is displayed in vitro with steroids, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21, retinoids and sugars as substrates, 2-propanedione as substrates, 3-Heptanedione and 1-Phenyl-1, 4-Hexanedione, Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
DHRS2, Dehydrogenase/reductase SDR family member 2, Dicarbonyl reductase HEP27, Protein D, SDR25C1, mitochondrial, HEP27 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
DHRS2 |
| Short name: |
DHRS2 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
dehydrogenase/reductase (SDR family) member 2 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DHRS2 and IDBG-3407 and ENSG00000100867 and 10202, Dhrs2 and IDBG-163262 and ENSMUSG00000022209 and 71412, HEP27 and SDR25C1, nuclei, oxidoreductase activity, this GO :0004090 and carbonyl reductase (NADPH) activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0005635 and nuclear envelope and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005759 and mitochondrial matrix and cellular component this GO :0008152 and metabolic process and biological process this GO :0008207 and C21-steroid hormone metabolic process and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009636 and response to toxic substance and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0034599 and cellular response to oxidative stress and biological process this GO :0043011 and myeloid dendritic cell differentiation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004090 : carbonyl reductase (NADPH) activity, this GO :0004090 : carbonyl reductase (NADPH) activity and also this GO :0016491 : oxidoreductase activity, this GO :0016491 : oxidoreductase activity, dehydrogenase/reductase (SDR family) member 2 |
| Identity: |
18349 |
| Gene: |
DHRS2 |
More about : DHRS2 |
| Long gene name: |
dehydrogenase/reductase 2 |
| Synonyms gene name: |
dehydrogenase/reductase (SDR family) member 2 |
| Synonyms: |
HEP27 SDR25C1 |
| Synonyms name: |
member 1 , short chain dehydrogenase/reductase family 25C |
| Locus: |
14q11, 2 |
| Discovery year: |
2002-04-26 |
| Entrez gene record: |
10202 |
| Pubmed identfication: |
7556196 11944995 16685466 19027726 |
| RefSeq identity: |
NM_182908 |
| Classification: |
Short chain dehydrogenase/reductase superfamily |
| Havana BLAST/BLAT: |
OTTHUMG00000028771 |