| Long name: |
Biotin Conjugated, KLF2/4 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
KLF2/4 |
| Specificity: |
This antibody may crossreact with KLF2 due to high sequence similarity, This is a highly specific antibody against KLF2/4 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
420-470/513 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from human KLF4 |
| Gene ID number: |
9314 |
| Swiss Prot: |
O43474 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds the 5'-CACCC-3' core sequence, Binds to the promoter region of its own gene and can activate its own transcription, Contributes to the down-regulation of p53/TP53 transcription, Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development, Plays an important role in maintaining embryonic stem cells, Regulates the expression of key transcription factors during embryonic development, Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface, and in preventing their differentiation, can act both as activator and as repressor, Transcription factor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
LKLF |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
KLF2/4 Conjugated |
| Short name: |
Conjugated, KLF2/4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Kruppel-like factor 2 (lung)/4 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0034101 and erythrocyte homeostasis and biological process this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0036003 and positive regulation of transcription from RNA polymerase II promoter in response to stress and biological process this GO :0040029 and regulation of gene expression, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0051247 and positive regulation of protein metabolic process and biological process this GO :0060509 and Type I pneumocyte differentiation and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0071356 and cellular response to tumor necrosis factor and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071409 and cellular response to cycloheximide and biological process this GO :0071499 and cellular response to laminar fluid shear stress and biological process this GO :1901653 and cellular response to peptide and biological process, KLF2 and IDBG-35485 and ENSG00000127528 and 10365, Klf2 and IDBG-167841 and ENSMUSG00000055148 and 16598, LKLF, epigenetic and biological process this GO :0043249 and erythrocyte maturation and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045893 and positive regulation of transcription, metal ion binding, nuclei, this GO :0000902 and cell morphogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0043565 : sequence-specific DNA binding and also this GO :0046872 : metal ion binding, this GO :0005515 : protein binding, this GO :0043565 : sequence-specific DNA binding, this GO :0046872 : metal ion binding, Kruppel-like factor 2 (lung) |
| Identity: |
6347 |
| Gene: |
KLF2 |
More about : KLF2 |
| Long gene name: |
Kruppel like factor 2 |
| Synonyms gene name: |
Kruppel-like factor 2 (lung) |
| Synonyms name: |
lung Kruppel-like factor |
| Locus: |
19p13, 11 |
| Discovery year: |
1999-12-14 |
| GenBank acession: |
AF123344 |
| Entrez gene record: |
10365 |
| Pubmed identfication: |
10217429 10458913 |
| Classification: |
Kruppel like factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000182330 |