| Long name: |
FITC Conjugated, Heparanase Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Heparanase |
| Specificity: |
This is a highly specific antibody against Heparanase |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Heparanase |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Heparanase is a heterodimer comprised of a 50 kDa subunit harboring the active site and an 8 kDa subunit, Heparanase is highly expressed in myeloid leukocytes (i, Heparanase plays an important role in ECM degradation, Human heparanase was found to be upregulated in various types of primary tumors, It is produced as a latent 65 kDa precursor and proteolytically processed to its active form, Upon degradation, correlating in some cases with increased tumor invasiveness and vascularity and with poor prospective survival, facilitating the migration and extravasations of tumor cells and inflammatory leukocytes, heparanase releases growth factors and cytokines that stimulate cell proliferation and chemotaxis, neutrophils) in platelets and in human placenta, which degrades heparan sulfate side chains of heparan sulfate proteoglycans (HSPGs) in the extracellular matrix, Heparanase is an endo-beta-D-glucuronidase, e |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
Endo glucoronidase, Endo glucoronidase, Endo-glucoronidase, HEP, HPA, HPR 1, HPR1, HPSE, HPSE 1, HPSE1, HPSE_HUMAN, HSE 1, HSE1, Heparanase 1, Heparanase1, Hpa 1, Hpa1, heparanase, heparanase 1, heparanase-1, heparanase1, Heparanase 50 kDa subunit |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Heparanase Conjugated |
| Short name: |
FITC Conjugated, Heparanase Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, Heparanase (Antibody to) |
| Alternative technique: |
antibodies |