| Long name: |
NALP6 Primary Polyclonal Antibody |
| Also known as: |
NALP6 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NALP6 |
| Specificity: |
This is a highly specific antibody against NALP6 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
395-425/892 |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NALP6 |
| Gene ID number: |
171389 |
| Swiss Prot: |
P59044 |
| Tested Applications: |
IHC-P |
| Recommended dilutions: |
IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds arginine-vasopressin but not angiotensin II and acts as an arginine-vasopressin V2 receptor, May mediate activation of CASP1 via ASC, Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential, Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, and/or cell cycle, apoptosis, glucose and lipid metabolism, inflammation-inducing bacteria such as Prevotella species, promote activation of NF-kappa-B and stimulate cAMP accumulation (By similarity), May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Angiotensin II/vasopressin receptor, CLR11, LRR and PYD domains-containing protein 6, NACHT, NALP6, NAVR, NAVR/AVR, NLRP6, PAN3, PYPAF5, PYRIN-containing APAF1-like protein 5, 4, AVR |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NALP6 |
| Short name: |
NALP6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
NALP6 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
22944 |
| Gene: |
NLRP6 |
More about : NLRP6 |
| Long gene name: |
NLR family pyrin domain containing 6 |
| Synonyms gene: |
NALP6 |
| Synonyms gene name: |
NACHT, leucine rich repeat and PYD containing 6 |
| Synonyms: |
PYPAF5 PAN3 CLR11, 4 |
| Synonyms name: |
leucine rich repeat and pyrin domain containing 6 , nucleotide-binding oligomerization domain |
| Locus: |
11p15, 5 |
| Discovery year: |
2003-10-28 |
| GenBank acession: |
AF479748 |
| Entrez gene record: |
171389 |
| Pubmed identfication: |
12563287 12019269 |
| RefSeq identity: |
NM_138329 |
| Classification: |
NLR family Pyrin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000119070 |