| Long name: |
Syntrophin-1+2+3 Primary Polyclonal Antibody |
| Also known as: |
Syntrophin-1+2+3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Syntrophin-1+2+3 |
| Specificity: |
This is a highly specific antibody against Syntrophin-1+2+3 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Syntrophin-1+2+3 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Jan 2013], The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1, This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues, This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS), This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes, This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue, [provided by RefSeq, 5, Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
59kDa dystrophin-associated protein A1 basic component 2, Beta-1-syntrophin, Beta-2-syntrophin, SNT1, SNT2, SNT3, SNTA1, SNTB1, SNTB1_HUMAN, SNTB2, SNTB2_HUMAN, Syntrophin alpha 1, Syntrophin beta 1, Syntrophin beta 2, Syntrophin-1, Syntrophin-2, Syntrophin-3, alpha-1-syntrophin, SNTA1_HUMAN |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Syntrophin-1+2+3 |
| Short name: |
Syntrophin-1+2+3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Syntrophin-1+2+3 (Antibody to) |
| Alternative technique: |
antibodies |