| Long name: |
Biotin Conjugated, c-ABL(Tyr115) Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
c-ABL Tyr115 |
| Specificity: |
This is a highly specific antibody against c-ABL Tyr115 |
| Modification: |
Phosphorylation |
| Modification site: |
Tyr115 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform a around the phosphorylation site of Tyr115 |
| Gene ID number: |
25 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Activity of c-Abl protein is negatively regulated by its SH3 domain, The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, The t(9, [provided by RefSeq], and deletion of the SH3 domain turns ABL1 into an oncogene, and stress response, cell adhesion, cell division, suggesting a cell cycle function for ABL1, with alternatively spliced first exons spliced to the common exons 2-11, 22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia, The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
ABL |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
c-ABL(Tyr115) Conjugated |
| Short name: |
Conjugated, c-ABL(Tyr115) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, c-ABL(Tyr115) (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7467 |
| Gene: |
MTTP |
More about : MTTP |
| Long gene name: |
microsomal triglyceride transfer protein |
| Synonyms gene: |
MTP |
| Synonyms gene name: |
88kD) microsomal triglyceride transfer protein (large polypeptide, 88kDa) , microsomal triglyceride transfer protein (large polypeptide |
| Locus: |
4q23 |
| Discovery year: |
1994-12-07 |
| Entrez gene record: |
4547 |
| Pubmed identfication: |
8111381 |
| Havana BLAST/BLAT: |
OTTHUMG00000131023 |