| Long name: |
ALEXA FLUOR 488 Conjugated, ECT2 (Ser370) Polyclonal Antibody |
| Also known as: |
Anti-ECT2 Ser370 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ECT2 Ser370 |
| Specificity: |
This is a highly specific antibody against ECT2 Ser370 |
| Modification: |
Phosphorylation |
| Modification Site: |
Ser370 |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic phosphopeptide derived from human ECT2 around the phosphorylation site of Ser370 |
| Gene ID Number: |
1894 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver, The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases, Thus, [provided by RefSeq], and is thought to have an important role in the regulation of cytokinesis, this protein is expressed in a cell cycle-dependent manner during liver regeneration, The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
ARHGEF31 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the ECT2 (Ser370) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
ECT2 (Ser370) |
| Short name: |
ECT2 (Ser370) Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, epithelial cell transforming sequence 2 oncogene (Ser370) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
ARHGEF31, BT, ECT2 and IDBG-65239 and ENSG00000114346 and 1894, Ect2 and IDBG-134125 and ENSMUSG00000027699 and 13605, nuclei, protein homodimerization activity, this GO :0000902 and cell morphogenesis and biological process this GO :0000910 and cytokinesis and biological process this GO :0004871 and signal transducer activity and molecular function this GO :0005085 and guanyl-nucleotide exchange factor activity and molecular function this GO :0005089 and Rho guanyl-nucleotide exchange factor activity and molecular function this GO :0005096 and GTPase activator activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0015031 and protein transport and biological process this GO :0017048 and Rho GTPase binding and molecular function this GO :0030496 and midbody and cellular component this GO :0032147 and activation of protein kinase activity and biological process this GO :0032154 and cleavage furrow and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032467 and positive regulation of cytokinesis and biological process this GO :0032862 and activation of Rho GTPase activity and biological process this GO :0032863 and activation of Rac GTPase activity and biological process this GO :0035023 and regulation of Rho protein signal transduction and biological process this GO :0042307 and positive regulation of protein import into nucleus and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043089 and positive regulation of Cdc42 GTPase activity and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045859 and regulation of protein kinase activity and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0051056 and regulation of small GTPase mediated signal transduction and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051988 and regulation of attachment of spindle microtubules to kinetochore and biological process this GO :0070301 and cellular response to hydrogen peroxide and biological process this GO :0070830 and tight junction assembly and biological process this GO :0071277 and cellular response to calcium ion and biological process this GO :0071479 and cellular response to ionizing radiation and biological process this GO :0072686 and mitotic spindle and cellular component this GO :0097149 and centralspindlin complex and cellular component this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0004871 : signal transducer activity, this GO :0004871 : signal transducer activity and also this GO :0005085 : guanyl-nucleotide exchange factor activity and also this GO :0005089 : Rho guanyl-nucleotide exchange factor activity and also this GO :0005096 : GTPase activator activity and also this GO :0005515 : protein binding and also this GO :0017048 : Rho GTPase binding and also this GO :0042803 : protein homodimerization activity, this GO :0005085 : guanyl-nucleotide exchange factor activity, this GO :0005089 : Rho guanyl-nucleotide exchange factor activity, this GO :0005096 : GTPase activator activity, this GO :0005515 : protein binding, this GO :0017048 : Rho GTPase binding, this GO :0042803 : protein homodimerization activity, 28366 and IDBG-636155 and ENSBTAG00000023814 and 100849477, 504746, epithelial cell transforming sequence 2 oncogene |
| Identity: |
3155 |
| Gene: |
ECT2 |
More about : ECT2 |
| Long gene name: |
epithelial cell transforming 2 |
| Synonyms gene name: |
epithelial cell transforming sequence 2 oncogene |
| Locus: |
3q26, 31 |
| Discovery year: |
1993-10-15 |
| GenBank acession: |
AA206473 |
| Entrez gene record: |
1894 |
| Pubmed identfication: |
8464478 10579713 |
| RefSeq identity: |
NM_018098 |
| Classification: |
Rho guanine nucleotide exchange factors |
| Havana BLAST/BLAT: |
OTTHUMG00000156762 |