| Long name: |
Cy5, 5 Conjugated, Chloride Channel 5 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Chloride Channel 5 |
| Specificity: |
This is a highly specific antibody against Chloride Channel 5 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Subcellular location: |
Mitochondrion |
| Source: |
KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
1p36 and 16p13, 3q28, 4q32, CLC1 is highly expressed in skeletal muscle, CLC2 is highly expressed in the epithelia of several organs including lung, CLC3 expression is particularly abundant in neuronal tissue, CLC6 and CLC7 are broadly expressed in several tissues including testis, CLCs regulate excitability in muscle and nerve cells, Mutations in the gene encoding CLC1 lead to myotonia, Mutations in the gene encoding CLC5 lead to Dentâ, The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, Xp11, Xp22, a critical component of all living cells, a renal disorder characterized by proteinuria and hypercalciuria, aid in organic solute transport and maintain cellular volume, an inheritable disorder characterized by muscle stiffness and renal salt wasting, brain and muscle, kidney, respectively, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain, &euro, &trade, 23-p11, 3, 22, The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, s disease |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
CLC5, CLCK2, CLCN5, CLCN5_HUMAN, Chloride transporter ClC-5, ClC-5, DENTS, H+/Cl- exchange transporter 5, NPHL1, NPHL2, XLRH, XRN, hCIC-K2, Chloride channel protein 5 |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
Chloride Channel 5 Conjugated |
| Short name: |
Conjugated, Chloride Channel 5 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, Chloride Channel 5 (Antibody to) |
| Alternative technique: |
antibodies |